Sign inSign up
Logo

ADSA Society

Logo
IssuesFor AuthorsAdvertisingNewsHelp

ADSA Society

Search Results

You are looking at 1-10 of 18

Figure 1. ; Schematic of the experimental protocol. Each rat was placed in a wire net container on a heated glass base 10 minutes prior to the start of the experiment. Baseline values were recorded 5 minutes prior to subcutaneous injection. Paw withdrawal latency was monitored immediately after the injection of the test solution; latency was then monitored every 5 minutes thereafter for 40 minutes.
Yukako Tsutsui and
 Katsuhisa Sunada
Figure 1. 
Figure 1. 

Schematic of the experimental protocol. Each rat was placed in a wire net container on a heated glass base 10 minutes prior to the start of the experiment. Baseline values were recorded 5 minutes prior to subcutaneous injection. Paw withdrawal latency was monitored immediately after the injection of the test solution; latency was then monitored every 5 minutes thereafter for 40 minutes.

Figure 2. ; Paw withdrawal latency over time. NS indicates normal saline; A, 4% articaine (2 mg); DA, 5 μg/kg dexmedetomidine (1.25 μg) + 4% articaine (2 mg); and EA, 1:100,000 epinephrine (0.9 μg) + 4% articaine (2 mg). Paw withdrawal latency was monitored from 0 to 40 minutes after injection; n = 11 per study group. *Statistically significant difference compared to baseline. †Statistically significant difference compared to NS. ‡Statistically significant difference compared to A.
Yukako Tsutsui and
 Katsuhisa Sunada
Figure 2. 
Figure 2. 

Paw withdrawal latency over time. NS indicates normal saline; A, 4% articaine (2 mg); DA, 5 μg/kg dexmedetomidine (1.25 μg) + 4% articaine (2 mg); and EA, 1:100,000 epinephrine (0.9 μg) + 4% articaine (2 mg). Paw withdrawal latency was monitored from 0 to 40 minutes after injection; n = 11 per study group. *Statistically significant difference compared to baseline. †Statistically significant difference compared to NS. ‡Statistically significant difference compared to A.

Adding Dexmedetomidine to Articaine Increases the Latency of Thermal Antinociception in Rats
Yukako Tsutsui DDS, PhD and
 Katsuhisa Sunada DDS, PhD
Article Category: Research Article
Volume/Issue: Volume 67: Issue 2
Online Publication Date: Jul 06, 2020
DOI: 10.2344/anpr-66-04-06
Page Range: 72 – 78

Download PDF
Nothing After Midnight?
Kyle J. Kramer DDS, MS
Article Category: Editorial
Volume/Issue: Volume 70: Issue 1
Online Publication Date: Mar 28, 2023
DOI: 10.2344/anpr-70-02-03
Page Range: 1 – 2

.13381 3.  Özaltun F, Zengin SÜ, Orhon Ergün M, Çorman Dinçer P, Umuroğlu T. Determination of the relationship between postoperative delirium development and analgesia nociception index values in

Commentary
Christine L. Quinn DDS, MS
Article Category: Article Commentary
Volume/Issue: Volume 67: Issue 4
Online Publication Date: Dec 31, 2020
DOI: 10.2344/anpr-67-04-08
Page Range: 245 – 247

mixture of local anesthetics (EMLA), which ultimately gained US Food and Drug Administration approval in 1992. EMLA (2.5% lidocaine and 2.5% prilocaine) is now widely used both as a topical cream for anesthesia prior to venipuncture or a gel for intraoral topical anesthesia. Another drug that Dr Yagiela discussed is capsaicin and its application for relief of chronic pain. Capsaicin provides a prolonged loss of nociception in an area wherever it is topically applied. The primary problem with capsaicin is that it causes acute pain upon initial application

Literature Review for Office-Based Anesthesia
Mark A. Saxen DDS, PhD
Article Category: Book Review
Volume/Issue: Volume 68: Issue 2
Online Publication Date: Jun 29, 2021
DOI: 10.2344/0003-3006-68.2.128
Page Range: 128 – 130

study, the report illustrates that avoidance of opioids may pose new risks that might not outweigh the known risks of opioids. It is noteworthy that all patients in this study received 9 other pharmacologic agents as part of their balanced anesthetic. Whether or not profound bradycardia or hypotension would occur with a simpler, streamlined balanced anesthetic technique remains unknown. Several other limitations of the report were described, including the lack of specific monitoring for depth of anesthesia and nociception and the fact that the optimal dosing

COMMENTARY
Stuart E. Lieblich DMD
Article Category: Article Commentary
Volume/Issue: Volume 64: Issue 3
Online Publication Date: Jan 01, 2017
DOI: 10.2344/0003-3006-64.3.125
Page Range: 125 – 126

, it is more effective than that administered after the surgery, ie, before nociception has started. Thus there is controversy as to whether there is a benefit to preemptively administered medications as opposed to preventive administration. 2 One could argue that taking a medication with potential gastrointestinal side effects, such as ibuprofen, on an empty stomach could cause more adverse effects than waiting until after surgery, while the local anesthetic is still effective, and taking the NSAID with a small amount of food. I presume that most of us in

A Survey of Pain, Pressure, and Discomfort Induced by Commonly Used Oral Local Anesthesia Injections
Eliezer Kaufman DMD,
 Joel B. Epstein DMD, MSD, FRCD(C),
 Eitan Naveh DSc,
 Meir Gorsky DMD,
 Anat Gross DMD, and
 Galit Cohen DMD
Article Category: Other
Volume/Issue: Volume 52: Issue 4
Online Publication Date: Jan 01, 2005
DOI: 10.2344/0003-3006(2005)52[122:ASP]2.0.CO;2
Page Range: 122 – 127

Local anesthetics (LAs) are the most widely used drugs in medicine and dentistry. 1 They prevent nociception generated during surgical and dental procedures, and without LAs, many medical and dental procedures could not be performed. The injection of LAs is often the only perceived painful part of the medical or dental procedure, and fear associated with LA injection has been reported to be a factor in avoiding dental treatment. 2 Numerous studies have examined possible variables that lead to this phenomenon. The purpose of this study was to assess the

Anesthetic Management of a Patient With Restless Legs Syndrome: A Case Report
Naohiro Ohshita DDS, PhD,
 Koji Yamagata PhD,
 Akio Himejima DDS, PhD,
 Kazuhiro Kaneda DDS, PhD,
 Teruyuki Yasutome DDS, PhD,
 Yoshiko Matsuda DDS, PhD,
 Yasuo M. Tsutsumi MD, PhD, and
 Yoshihiro Momota DDS, PhD
Article Category: Case Report
Volume/Issue: Volume 67: Issue 4
Online Publication Date: Dec 31, 2020
DOI: 10.2344/anpr-67-02-10
Page Range: 226 – 229

postoperative respiratory depression. In this case, dexamethasone was used as a supplement for postoperative edema, but ideally non-steroidal anti-inflammatory drugs could have also been administered for additional management of postoperative swelling and pain. Dexmedetomidine is associated with spinal nociceptive processing and, unlike fentanyl, enhances the descending inhibition and decreases the descending facilitation to modulate pain and nociception. 13 As an α2-agonist, dexmedetomidine produces potent antinociceptive effects and reduces release of the spinal

Dexmedetomidine Increases the Latency of Thermal Antinociception in Rats
Yukako Tsutsui DDS, PhD and
 Katsuhisa Sunada DDS, PhD
Article Category: Research Article
Volume/Issue: Volume 64: Issue 4
Online Publication Date: Jan 01, 2017
DOI: 10.2344/anpr-65-01-08
Page Range: 230 – 234

Hargreaves K, Dubner R, Brown F, Flores C, Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia . Pain . 1988 ; 32 : 77 – 88 . 10 Yamamoto

ANPR logo
AboutIssuesAuthor InformationSubscriptions
PermissionsAdvertisingPrivacy PolicyFacebook
TwitterFAQHelp

ADSA Society

eISSN: 1878-7177

ISSN: 0003-3006

Powered by PubFactory